Ehlers-Danlos Syndrome
Classical Ehlers-Danlos Syndrome
cEDS
Classical EDS features marked skin hyperextensibility, widened atrophic scars, and joint hypermobility. It is often associated with pathogenic variants in COL5A1 or COL5A2 affecting type V collagen. Wound healing complications and tissue fragility warrant careful surgical and trauma precautions.
- Prevalence
- 1 in 20,000-40,000
- Inheritance
- Autosomal dominant (often COL5A1/COL5A2)
- Screened at Birth
- No
- On RUSP
- No
About This Data
This disorder is part of the Cureledger rare disease data corpus. We are building privacy-preserving natural history datasets and advocacy tools for rare disease communities. Data is maintained by clinical advisors and the patient community.