HemoglobinopathiesNewborn ScreeningRUSP
Sickle Beta-Thalassemia
SĪ²-thal
Sickle beta-thalassemia combines sickle hemoglobin with beta-thalassemia mutations, producing variable severity between sickle trait and sickle cell anemia depending on beta-globin output. Clinical management resembles other sickling disorders with attention to pain crises, infection prevention, and transfusion indications. Screening programs detect hemoglobin patterns at birth for timely referral.
- Prevalence
- Varies by ethnicity and region
- Inheritance
- Autosomal recessive
- Screened at Birth
- Yes
- On RUSP
- Yes (Recommended Uniform Screening Panel)
About This Data
This disorder is part of the Cureledger rare disease data corpus. We are building privacy-preserving natural history datasets and advocacy tools for rare disease communities. Data is maintained by clinical advisors and the patient community.