Ehlers-Danlos Syndrome
Vascular Ehlers-Danlos Syndrome
vEDS
Vascular EDS is caused by pathogenic variants in COL3A1 and carries the highest risk of arterial, uterine, and hollow-organ rupture among EDS types. The clinical picture may include thin skin, easy bruising, and a characteristic facial appearance, but severity varies. Patients benefit from specialized multidisciplinary care and avoidance of invasive procedures when alternatives exist.
- Prevalence
- 1 in 50,000-200,000
- Inheritance
- Autosomal dominant (COL3A1)
- Screened at Birth
- No
- On RUSP
- No
About This Data
This disorder is part of the Cureledger rare disease data corpus. We are building privacy-preserving natural history datasets and advocacy tools for rare disease communities. Data is maintained by clinical advisors and the patient community.